Magma ATF Screening System

Coming Q4 2026

Magma ATF Screening System ATFSS

Any Filter. High-Throughput. Save Media.

The Magma ATF Screening System (ATFSS) is an open-architecture platform designed for rapid, low-volume screening of hollow-fiber filters and media in bioprocessing. It enables side-by-side comparison of filter membranes at culture volumes as low as 100 mL, giving labs high-quality scale-up data without the high media costs, vendor lock-in, or rigid configurations of traditional systems.

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Magma ATF Screening System PDF
Magma ATF Screening System ATFSS

Key System Benefits

True Open-Architecture Compatibility

  • Break free from proprietary consumable lock-in.
  • Validate and run hollow-fiber membranes from any supplier.
  • Accelerate second-sourcing initiatives and safeguard your bioprocess supply chain.

60%+ Reduction in Media Consumption

  • Operates effectively at working volumes as low as 100 mL (compared to legacy requirements of 250 mL–1 L).
  • Dramatically cuts costs on expensive specialized perfusion media during early-stage screening.

Characterize Filter Fouling and Flux

  • Side-by-side screening of multiple membranes before you scale up.
  • Flawlessly maintained cultures exceeding 40 × 10⁶ cells/mL with stable flux and zero mechanical fouling.


Engineered for High-Reliability, Cost Efficient Operations

  • Trusted Pedigree: Engineered by the same team behind commercialized Normal Flow and traditional TFF Screening Systems.
  • Direct, robust mechanics eliminate the need for mandatory $8,000–$15,000 annual controller service contracts.

Magma ATFSS Software Home Screen

See Every System, One Screen

  • Windows PC based Graphic User Interface
  • View key data from all systems on a “dashboard view”
  • A Trends Module where the data can be viewed and graphs exported
  • All data from a run is written to a file real-time

Flexible Configurations That Match Your Workflow

Screen multiple parameters side by side to establish precise flux, shear, and fouling profiles before investing in pilot-scale volumes.

High-Throughput Membrane & Condition Screening

  • Setup: Single bioreactor manifold feeding 2 to 4 parallel ATF systems.
  • Ideal for: Direct, head-to-head membrane comparison, crossflow velocity optimization, and side-by-side fouling metrics under identical culture conditions.
ATFSS-Single Bioreactor with 4 Filter Systems

Parallel Process Development

  • Setup: Up to 4 independent ATF systems, each paired with its own dedicated mini-bioreactor.
  • Ideal for: Multi-variable experimental design (DoE), parallel clone evaluation, and testing distinct media formulations simultaneously.
ATFSS-4 Filter Systems Each with a Bioreactor

Technical Specifications Overview

  • Working Volume Range: 6 mL, 20 mL, and 50 mL pump-head sizes (optimized for low-volume screening)
  • Membrane Format: Standard hollow-fiber modules (universal connectivity)
  • System Channels: 2 to 4 parallel processing lines
  • Controller Interface: Open digital architecture with automated data logging
  • Preventative Maintenance: User-serviceable fluidics; no forced vendor maintenance tiers
  • Dimensions (DxWxH): 9in x 2.6in x 11.5in
Magma ATF Screening System Stand
Magma ATF Screening System Stand